Search results for "density [energy]"
showing 10 items of 138 documents
Extended Entropy Functional for Nonlinear Systems in Stochastic Dynamics
2002
Adaptive design optimization: a mutual information-based approach to model discrimination in cognitive science.
2010
Discriminating among competing statistical models is a pressing issue for many experimentalists in the field of cognitive science. Resolving this issue begins with designing maximally informative experiments. To this end, the problem to be solved in adaptive design optimization is identifying experimental designs under which one can infer the underlying model in the fewest possible steps. When the models under consideration are nonlinear, as is often the case in cognitive science, this problem can be impossible to solve analytically without simplifying assumptions. However, as we show in this letter, a full solution can be found numerically with the help of a Bayesian computational trick d…
Traffic simulation models calibration using speed–density relationship: An automated procedure based on genetic algorithm
2016
Calibration of traffic models.Calibration as optimization problem.Use of genetic algorithm. This paper presents the first results of a research which applied a genetic algorithm to calibrate a microscopic traffic simulation model based on speed-density relationships. A large set of traffic data collected from the A22 Freeway, Italy, was used and a comparison was performed between the field measurements and the simulation outputs obtained for a test freeway segment by using the Aimsun microscopic simulator.The calibration was formulated as an optimization problem to be solved based on a genetic algorithm; the objective function was defined in order to minimize the differences between the sim…
A Novel Multi-hop Broadcasting Method for VANETs Based on Autonomic Computing Paradigm
2014
One of the three best papers, Selected for the Annals of Telecommunications journal; International audience; Broadcasting is widely used in Vehicular Ad hoc Networks (VANETs) but it is hard to achieve efficiently since it depends on the network density, i.e. may cause network congestion if the protocols are not well designed. This paper introduces a novel Autonomic Dissemination Method (ADM) which delivers messages in accordance with given priority and density levels. The proposed approach is based on two steps: an offline optimization process and an online adaptation to the network characteristics. The aim is to make effective use of radio resources when there are many messages to send imu…
Probabilistic Selection Approaches in Decomposition-based Evolutionary Algorithms for Offline Data-Driven Multiobjective Optimization
2022
In offline data-driven multiobjective optimization, no new data is available during the optimization process. Approximation models, also known as surrogates, are built using the provided offline data. A multiobjective evolutionary algorithm can be utilized to find solutions by using these surrogates. The accuracy of the approximated solutions depends on the surrogates and approximations typically involve uncertainties. In this paper, we propose probabilistic selection approaches that utilize the uncertainty information of the Kriging models (as surrogates) to improve the solution process in offline data-driven multiobjective optimization. These approaches are designed for decomposition-base…
The human peroxisome in health and disease: The story of an oddity becoming a vital organelle
2013
Abstract Since the first report by Rhodin in 1954, our knowledge on mammalian microbodies/peroxisomes has known several periods. An initial two decades period (1954–1973) has contributed to the biochemical individualisation of peroxisomes as a new class of subcellular organelles (de Duve, 1965). The corresponding research period failed to define a clear role of mammalian peroxisomes in vital functions and intermediary metabolism, explaining why feeling that peroxisomes might be in the human cell oddities has prevailed during several decades. The period standing from 1973 to nowadays has progressively removed this cell oddity view of peroxisomes by highlighting vital function and metabolic r…
In Vitro Release of Lectins From Phallusia mamillata Hemocytes After Their Fractionation on a Density Gradient
1993
Hemocytes were fractionated by centrifugation on a discontinuous Percoll density gradient from the hemolymph of Phallusia mamillata. Results obtained from microcultures of the fractionated hemocytes, sugar-inhibition experiments, SDS-PAGE, and immunoblotting indicate that “compartment cells” release cellular-type (CL) lectins that are specific for α-lactose and lactulose. The released lectins have the same properties as the CL lectins that were previously isolated from sonicated unfractionated hemocytes, but they differ in terms of some molecular and immunological properties from the lectins (SL) purified from the serum. SLs were never found in the supernatants from microcultures of the fra…
The structure of cosmic voids in a LCDM Universe
2013
Eulerian cosmological codes are especially suited to properly describe the low density regions. This property makes this class of codes excellent tools to study the formation and evolution of cosmic voids. Following such ideas, we present the results of an Eulerian adaptive mesh refinement (AMR) hydrodynamical and N-body simulation, that contrary to the common practice, has been designed to refine the computational grid in the underdense regions of the simulated volume. Thus, the void regions are better described due to the combined effect of the Eulerian character of the numerical technique and the use of high numerical resolution from the AMR approach. To analyse the outcome of this simul…
Isolation and purification of plasmids from Bacteroides fragilis using rubidium trichloroacetate density gradient centrifugation.
1983
A rapid and easy final purification method is described for the isolation of plasmids from B. fragilis. Using RbTCA density gradient centrifugation in an airfuge ultracentrifuge ccc plasmid DNA can be separated from RNA, residual chromosomal DNA, linear and oc plasmid DNA. Pure ccc plasmid DNA is obtained from cultures of between 1 ml and 2 l in less than one day.
Cell cooperation in coelomocyte cytotoxic activity of Paracentrotus lividus coelomocytes
2007
The coelomic fluid from the sea urchin Paracentrotus lividus contains several coelomocyte types including amoebocytes and uncoloured spherulocytes involved in immune defences. In the present paper, we show a Ca(2+)-dependent cytotoxic activity for the unfractionated coelomocytes assayed in vitro, with rabbit erythrocytes and the K562 tumour cell line. In a plaque-forming assay, whole coelomocyte preparations as well as density gradient separated coelomocyte populations revealed that cell populations enriched in uncoloured spherulocytes, exerted high cytotoxic activity by releasing lysins in the presence of amoebocytes. This cooperative effect could be dependent on soluble factors released b…